Duffy binding proteins

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Duffy binding domain
PDB 1zro EBI.jpg
crystal structure of eba-175 region ii (rii) crystallized in the presence of (alpha)2,3-sialyllactose
Symbol Duffy_binding
Pfam PF05424
Pfam clan CL0195
InterPro IPR008602
Duffy binding protein N terminal
Symbol DuffyBP_N
Pfam PF12377
InterPro IPR021032

In molecular biology, Duffy binding proteins are found in plasmodia. Plasmodium vivax and Plasmodium knowlesi merozoites invade Homo sapiens erythrocytes that express Duffy blood group surface determinants. The Duffy receptor family is localised in micronemes, an organelle found in all organisms of the phylum Apicomplexa.[1][2]

See also[edit]


  1. ^ Adams JH, Hudson DE, Torii M, Ward GE, Wellems TE, Aikawa M, Miller LH (October 1990). "The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites". Cell 63 (1): 141–53. doi:10.1016/0092-8674(90)90295-P. PMID 2170017. 
  2. ^ Babaeekho, L.; Zakeri, S.; Djadid, N. D. (2009). "Genetic mapping of the duffy binding protein (DBP) ligand domain of Plasmodium vivax from unstable malaria region in the Middle East". The American journal of tropical medicine and hygiene 80 (1): 112–118. PMID 19141848.  edit

This article incorporates text from the public domain Pfam and InterPro IPR008602