EAL domain

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EAL domain
PDB 2bas EBI.jpg
crystal structure of the bacillus subtilis ykui protein, with an eal domain.
Identifiers
Symbol EAL
Pfam PF00563
InterPro IPR001633
CDD cd01948

In molecular biology, the EAL domain is a conserved protein domain. It is found in diverse bacterial signalling proteins. It is named EAL after its conserved residues. The EAL domain may function as a diguanylate phosphodiesterase.[1] The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.

References[edit]

  1. ^ Galperin MY, Nikolskaya AN, Koonin EV (September 2001). "Novel domains of the prokaryotic two-component signal transduction systems". FEMS Microbiol. Lett. 203 (1): 11–21. doi:10.1016/S0378-1097(01)00326-3. PMID 11557134. 

This article incorporates text from the public domain Pfam and InterPro IPR001633