Epstein–Barr virus latent membrane protein 2
LMP-2A/LMP-2B are transmembrane proteins that act to block tyrosine kinase signaling. It is believed that they act to inhibit activation of the viral lytic cycle. It s unknown whether LMP-2B is required for EBV-mediated growth transformation, while different groups have reported that LMP-2A alternatively is, or is not needed for transformation.
- Lynch DT, Zimmerman JS, Rowe DT (May 2002). "Epstein-Barr virus latent membrane protein 2B (LMP2B) co-localizes with LMP2A in perinuclear regions in transiently transfected cells". J. Gen. Virol. 83 (Pt 5): 1025–35. PMID 11961256.
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