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Enhancer of mRNA decapping 3
Protein EDC3 PDB 2VC8.png
Rendering based on PDB 2VC8.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols EDC3 ; LSM16; YJDC; YJEFN2
External IDs OMIM609842 MGI2142951 HomoloGene11827 GeneCards: EDC3 Gene
RNA expression pattern
PBB GE EDC3 219207 at tn.png
More reference expression data
Species Human Mouse
Entrez 80153 353190
Ensembl ENSG00000179151 ENSMUSG00000038957
UniProt Q96F86 Q8K2D3
RefSeq (mRNA) NM_001142443 NM_153799
RefSeq (protein) NP_001135915 NP_722494
Location (UCSC) Chr 15:
74.92 – 74.99 Mb
Chr 9:
57.71 – 57.75 Mb
PubMed search [1] [2]

Enhancer of mRNA-decapping protein 3 is a protein that in humans is encoded by the EDC3 gene.[1][2][3]

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005).[supplied by OMIM][3]


  1. ^ Albrecht M, Lengauer T (Jun 2004). "Novel Sm-like proteins with long C-terminal tails and associated methyltransferases". FEBS Lett 569 (1–3): 18–26. doi:10.1016/j.febslet.2004.03.126. PMID 15225602. 
  2. ^ Rudolph C, Sigruener A, Hartmann A, Orso E, Bals-Pratsch M, Gronwald W, Seifert B, Kalbitzer HR, Verdorfer I, Luetjens CM, Ortmann O, Bornstein SR, Schmitz G (May 2007). "ApoA-I-binding protein (AI-BP) and its homologues hYjeF_N2 and hYjeF_N3 comprise the YjeF_N domain protein family in humans with a role in spermiogenesis and oogenesis". Horm Metab Res 39 (5): 322–35. doi:10.1055/s-2007-977699. PMID 17533573. 
  3. ^ a b "Entrez Gene: EDC3 enhancer of mRNA decapping 3 homolog (S. cerevisiae)". 

Further reading[edit]