EDC3

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Enhancer of mRNA decapping 3 homolog (S. cerevisiae)
Protein EDC3 PDB 2VC8.png
Rendering based on PDB 2VC8.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols EDC3 ; LSM16; YJDC; YJEFN2
External IDs OMIM609842 MGI2142951 HomoloGene11827 GeneCards: EDC3 Gene
RNA expression pattern
PBB GE EDC3 219207 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 80153 353190
Ensembl ENSG00000179151 ENSMUSG00000038957
UniProt Q96F86 Q8K2D3
RefSeq (mRNA) NM_001142443 NM_153799
RefSeq (protein) NP_001135915 NP_722494
Location (UCSC) Chr 15:
74.92 – 74.99 Mb
Chr 9:
57.71 – 57.75 Mb
PubMed search [1] [2]

Enhancer of mRNA-decapping protein 3 is a protein that in humans is encoded by the EDC3 gene.[1][2][3]

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005).[supplied by OMIM][3]

References[edit]

  1. ^ Albrecht M, Lengauer T (Jun 2004). "Novel Sm-like proteins with long C-terminal tails and associated methyltransferases". FEBS Lett 569 (1–3): 18–26. doi:10.1016/j.febslet.2004.03.126. PMID 15225602. 
  2. ^ Rudolph C, Sigruener A, Hartmann A, Orso E, Bals-Pratsch M, Gronwald W, Seifert B, Kalbitzer HR, Verdorfer I, Luetjens CM, Ortmann O, Bornstein SR, Schmitz G (May 2007). "ApoA-I-binding protein (AI-BP) and its homologues hYjeF_N2 and hYjeF_N3 comprise the YjeF_N domain protein family in humans with a role in spermiogenesis and oogenesis". Horm Metab Res 39 (5): 322–35. doi:10.1055/s-2007-977699. PMID 17533573. 
  3. ^ a b "Entrez Gene: EDC3 enhancer of mRNA decapping 3 homolog (S. cerevisiae)". 

Further reading[edit]