EHF (gene)

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Ets homologous factor
Identifiers
Symbols EHF ; ESE3; ESE3B; ESEJ
External IDs OMIM605439 MGI1270840 HomoloGene7301 GeneCards: EHF Gene
RNA expression pattern
PBB GE EHF 219850 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 26298 13661
Ensembl ENSG00000135373 ENSMUSG00000012350
UniProt Q9NZC4 O70273
RefSeq (mRNA) NM_001206615 NM_007914
RefSeq (protein) NP_001193544 NP_031940
Location (UCSC) Chr 11:
34.64 – 34.68 Mb
Chr 2:
103.26 – 103.3 Mb
PubMed search [1] [2]

ETS homologous factor is a protein that in humans is encoded by the EHF gene.[1][2]

This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be associated with asthma susceptibility. This protein may be involved in epithelial differentiation and carcinogenesis.[2]

References[edit]

  1. ^ Kleinbaum LA, Duggan C, Ferreira E, Coffey GP, Buttice G, Burton FH (Nov 1999). "Human chromosomal localization, tissue/tumor expression, and regulatory function of the ets family gene EHF". Biochem Biophys Res Commun 264 (1): 119–26. doi:10.1006/bbrc.1999.1493. PMID 10527851. 
  2. ^ a b "Entrez Gene: EHF ets homologous factor". 

Further reading[edit]

External links[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.