EIF3F

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Eukaryotic translation initiation factor 3, subunit F
Identifiers
Symbols EIF3F ; EIF3S5; eIF3-p47
External IDs OMIM603914 MGI1913335 HomoloGene2783 GeneCards: EIF3F Gene
EC number 3.4.19.12
Orthologs
Species Human Mouse
Entrez 8665 66085
Ensembl ENSG00000175390 ENSMUSG00000031029
UniProt O00303 Q9DCH4
RefSeq (mRNA) NM_003754 NM_025344
RefSeq (protein) NP_003745 NP_079620
Location (UCSC) Chr 11:
7.99 – 8.02 Mb
Chr 7:
108.93 – 108.94 Mb
PubMed search [1] [2]

Eukaryotic translation initiation factor 3 subunit F is a protein that in humans is encoded by the EIF3F gene.[1][2]


Interactions[edit]

EIF3F has been shown to interact with Mammalian target of rapamycin[3] and EIF3A.[4][5][6]

References[edit]

  1. ^ Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J Biol Chem 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143. 
  2. ^ "Entrez Gene: EIF3S5 eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa". 
  3. ^ Harris, Thurl E; Chi An; Shabanowitz Jeffrey; Hunt Donald F; Rhoads Robert E; Lawrence John C (Apr 2006). "mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin". EMBO J. (England) 25 (8): 1659–68. doi:10.1038/sj.emboj.7601047. ISSN 0261-4189. PMC 1440840. PMID 16541103. 
  4. ^ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. 
  5. ^ Mayeur, Greg L; Fraser Christopher S; Peiretti Franck; Block Karen L; Hershey John W B (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. (Germany) 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. ISSN 0014-2956. PMID 14519125. 
  6. ^ Block, K L; Vornlocher H P; Hershey J W (Nov 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. (UNITED STATES) 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. ISSN 0021-9258. PMID 9822659. 

Further reading[edit]