EIF3I

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Eukaryotic translation initiation factor 3, subunit I
Identifiers
Symbols EIF3I ; EIF3S2; PRO2242; TRIP-1; TRIP1; eIF3-beta; eIF3-p36
External IDs OMIM603911 MGI1860763 HomoloGene2786 GeneCards: EIF3I Gene
RNA expression pattern
PBB GE EIF3S2 208756 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8668 54709
Ensembl ENSG00000084623 ENSMUSG00000028798
UniProt Q13347 Q9QZD9
RefSeq (mRNA) NM_003757 NM_018799
RefSeq (protein) NP_003748 NP_061269
Location (UCSC) Chr 1:
32.69 – 32.7 Mb
Chr 4:
129.59 – 129.6 Mb
PubMed search [1] [2]

Eukaryotic translation initiation factor 3 subunit I is a protein that in humans is encoded by the EIF3I gene.[1][2][3]

Interactions[edit]

EIF3I has been shown to interact with TGF beta 1[4] and EIF3A.[2][5][6]

References[edit]

  1. ^ Chen RH, Miettinen PJ, Maruoka EM, Choy L, Derynck R (Nov 1995). "A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor". Nature 377 (6549): 548–52. doi:10.1038/377548a0. PMID 7566156. 
  2. ^ a b Asano K, Kinzy TG, Merrick WC, Hershey JW (Feb 1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3". J. Biol. Chem. 272 (2): 1101–9. doi:10.1074/jbc.272.2.1101. PMID 8995409. 
  3. ^ "Entrez Gene: EIF3S2 eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa". 
  4. ^ Choy L, Derynck R (Nov 1998). "The type II transforming growth factor (TGF)-beta receptor-interacting protein TRIP-1 acts as a modulator of the TGF-beta response". J. Biol. Chem. 273 (47): 31455–62. doi:10.1074/jbc.273.47.31455. PMID 9813058. 
  5. ^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. 
  6. ^ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125. 

Further reading[edit]