EIF3S6

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Eukaryotic translation initiation factor 3, subunit E
Identifiers
Symbols EIF3E ; EIF3-P48; EIF3S6; INT6; eIF3-p46
External IDs OMIM602210 MGI99257 HomoloGene1205 GeneCards: EIF3E Gene
RNA expression pattern
PBB GE EIF3S6 208697 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3646 16341
Ensembl ENSG00000104408 ENSMUSG00000022336
UniProt P60228 P60229
RefSeq (mRNA) NM_001568 NM_008388
RefSeq (protein) NP_001559 NP_032414
Location (UCSC) Chr 8:
109.21 – 109.45 Mb
Chr 15:
43.25 – 43.28 Mb
PubMed search [1] [2]

Eukaryotic translation initiation factor 3 subunit E is a protein that in humans is encoded by the EIF3E gene.[1][2][3]


Interactions[edit]

EIF3S6 has been shown to interact with TRIM27,[4] EIF3A,[5][6][7] BAT2,[8] COPS6[9] and CSN3.[9]

References[edit]

  1. ^ Miyazaki S, Imatani A, Ballard L, Marchetti A, Buttitta F, Albertsen H, Nevanlinna HA, Gallahan D, Callahan R (January 1998). "The chromosome location of the human homolog of the mouse mammary tumor-associated gene INT6 and its status in human breast carcinomas". Genomics 46 (1): 155–8. doi:10.1006/geno.1997.4996. PMID 9403073. 
  2. ^ Asano K, Merrick WC, Hershey JW (October 1997). "The translation initiation factor eIF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome". J Biol Chem 272 (38): 23477–80. doi:10.1074/jbc.272.38.23477. PMID 9295280. 
  3. ^ "Entrez Gene: EIF3S6 Eukaryotic translation initiation factor 3, subunit 6 48kDa". 
  4. ^ Morris-Desbois, C; Bochard V; Reynaud C; Jalinot P (October 1999). "Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies". J. Cell. Sci. (ENGLAND) 112 (19): 3331–42. ISSN 0021-9533. PMID 10504338. 
  5. ^ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. 
  6. ^ Mayeur, Greg L; Fraser Christopher S; Peiretti Franck; Block Karen L; Hershey John W B (October 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. (Germany) 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. ISSN 0014-2956. PMID 14519125. 
  7. ^ Morris-Desbois, C; Réty S; Ferro M; Garin J; Jalinot P (December 2001). "The human protein HSPC021 interacts with Int-6 and is associated with eukaryotic translation initiation factor 3". J. Biol. Chem. (United States) 276 (49): 45988–95. doi:10.1074/jbc.M104966200. ISSN 0021-9258. PMID 11590142. 
  8. ^ Lehner, Ben; Semple Jennifer I; Brown Stephanie E; Counsell Damian; Campbell R Duncan; Sanderson Christopher M (January 2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics (United States) 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. ISSN 0888-7543. PMID 14667819. 
  9. ^ a b Hoareau Alves, Karine; Bochard Valérie; Réty Stéphane; Jalinot Pierre (September 2002). "Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome". FEBS Lett. (Netherlands) 527 (1–3): 15–21. doi:10.1016/S0014-5793(02)03147-2. ISSN 0014-5793. PMID 12220626. 

Further reading[edit]