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Eukaryotic translation initiation factor 4E nuclear import factor 1
Symbols EIF4ENIF1 ; 4E-T; Clast4
External IDs OMIM607445 MGI1921453 HomoloGene10522 GeneCards: EIF4ENIF1 Gene
RNA expression pattern
PBB GE EIF4ENIF1 218626 at tn.png
More reference expression data
Species Human Mouse
Entrez 56478 74203
Ensembl ENSG00000184708 ENSMUSG00000020454
UniProt Q9NRA8 Q9EST3
RefSeq (mRNA) NM_001164501 NM_001166547
RefSeq (protein) NP_001157973 NP_001160019
Location (UCSC) Chr 22:
31.83 – 31.89 Mb
Chr 11:
3.2 – 3.24 Mb
PubMed search [1] [2]

Eukaryotic translation initiation factor 4E transporter is a protein that in humans is encoded by the EIF4ENIF1 gene.[1][2]

The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic;its own nuclear import is regulated by a nuclear localization signal and nuclear export signals.[2]


EIF4ENIF1 has been shown to interact with EIF4E.[1]


Further reading[edit]