EIF4ENIF1

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Eukaryotic translation initiation factor 4E nuclear import factor 1
Identifiers
Symbols EIF4ENIF1 ; 4E-T; Clast4
External IDs OMIM607445 MGI1921453 HomoloGene10522 GeneCards: EIF4ENIF1 Gene
RNA expression pattern
PBB GE EIF4ENIF1 218626 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 56478 74203
Ensembl ENSG00000184708 ENSMUSG00000020454
UniProt Q9NRA8 Q9EST3
RefSeq (mRNA) NM_001164501 NM_001166547
RefSeq (protein) NP_001157973 NP_001160019
Location (UCSC) Chr 22:
31.83 – 31.89 Mb
Chr 11:
3.2 – 3.24 Mb
PubMed search [1] [2]

Eukaryotic translation initiation factor 4E transporter is a protein that in humans is encoded by the EIF4ENIF1 gene.[1][2]

The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic;its own nuclear import is regulated by a nuclear localization signal and nuclear export signals.[2]

Interactions[edit]

EIF4ENIF1 has been shown to interact with EIF4E.[1]

References[edit]

Further reading[edit]