EMD-386,088

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EMD-386,088
EMD386088.png
Systematic (IUPAC) name
5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
Clinical data
Legal status
?
Identifiers
CAS number 54635-62-0 YesY
ATC code None
PubChem CID 10131112
Chemical data
Formula C14H14ClN2 
Mol. mass 245.727 g/mol
 YesY (what is this?)  (verify)

EMD-386,088 is an indole derivative which is used in scientific research. It acts as a potent and selective 5-HT6 receptor agonist, with a Ki of 1 nM, a significantly higher affinity than older 5-HT6 agonists such as EMDT, although it possesses moderate affinity for the 5-HT3 receptor as well.[1]

See also[edit]

References[edit]

  1. ^ Mattsson, C; Sonesson, C; Sandahl, A; Greiner, HE; Gassen, M; Plaschke, J; Leibrock, J; Böttcher, H (2005). "2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists". Bioorganic & Medicinal Chemistry Letters 15 (19): 4230–4. doi:10.1016/j.bmcl.2005.06.067. PMID 16055331.