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Endoplasmic reticulum protein 29
PBB Protein ERP29 image.jpg
PDB rendering based on 1g7e.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols ERP29 ; C12orf8; ERp28; ERp31; HEL-S-107; PDI-DB; PDIA9
External IDs OMIM602287 MGI1914647 HomoloGene4963 GeneCards: ERP29 Gene
RNA expression pattern
PBB GE ERP29 201216 at tn.png
More reference expression data
Species Human Mouse
Entrez 10961 67397
Ensembl ENSG00000089248 ENSMUSG00000029616
UniProt P30040 P57759
RefSeq (mRNA) NM_001034025 NM_026129
RefSeq (protein) NP_001029197 NP_080405
Location (UCSC) Chr 12:
112.45 – 112.46 Mb
Chr 5:
121.43 – 121.45 Mb
PubMed search [1] [2]

Endoplasmic reticulum protein 29 (ERp29) is a chaperone protein that in humans is encoded by the ERP29 gene.[1]


ERp29 is a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide-isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.[1]


Further reading[edit]