|This article relies largely or entirely upon a single source. (December 2012)|
|Directed by||S. P. Jananathan|
|Produced by||R. B. Choudary|
|Written by||S. P. Jananathan
N. Kalyana Krishnan
|Music by||Srikanth Deva|
|Cinematography||N. K. Ekambaram|
|Edited by||N. Ganesh Kumar|
|Distributed by||Super Good Films|
|Release dates||20 October 2006|
|Running time||150 Minutes|
E (English: The Fly) is a 2006 Tamil Medical Thriller film directed by S.P.Jananathan, who won the Indian National Award in 2004 for his debut, Iyarkai. Jiiva, Nayantara, Karunaas and Pasupathy play lead roles. The film's music is composed by director, Srikanth Deva  son of Deva.The film was appreciated for its fresh storyline.
The movie revolves around Easwaran alias E (Jiiva), an orphan brought up in the musty, teeming slums of Chennai by an old woman. For him money is the thing in life, he does anything for that. He Comes across Jothy (Nayantara), a bar dancer, who settles down in the same locality. After a few encounters they get acquainted with each other. E's simple ways attract Jothy.
Coming to know of his past, Jothy tries desperate to correct his ways and set him on the right path. Meanwhile Dr Ramakrishnan (Ashish Vidyarthi) takes up the task of testing a medicine devised by a foreign company, which may come handy in killing people in thousands especially during times of wars. Dr Ramakrishnan chooses Jothy's sister and E's grandmother as specimen for the test. He cashes in on the ignorance to slum-dwellers. Things take a turn, when E rescues Dr Ramakrishnan from a murder bid by Nellai Mani (Pasupathy).
A sequence of events brings Nellai Mani and E together. Without knowing his motive, E hides him in a secret place and decides to hand him over to Dr Ramakrishnan for a huge sum. Slowly E gets attracted by good ways of Nellai Mani. Through him, E comes to know of Ramakrishnan's ulterior motives. Nellai Mani, a revolutionary fighting for a cause, tries to bring about a change in E's heart. Succeeding in his attempt, Nellai Mani lays down his life leaving E to complete his task. The rest is all about E's show all the way in putting an end to Ramakrishnan and his evil ways.
- Jiiva as Easwaran
- Nayantara as Jothy
- Pasupathy as Nellai Mani
- Ashish Vidyarthi as Dr. Ramakrishnan
- Karunas as Tony
- Ajay Rathnam
- Suruli Manohar
- Scissor Manohar
- Chaams as Ganeshan
- Sabitha Anand
- Attakathi Dinesh
|This section requires expansion. (December 2012)|
The film was a commercial success grossing $2 million at the box office.