The East Slovak Museum (Slovak: Východoslovenské múzeum) in Košice, Slovakia, is one of the oldest Slovak museums; it was founded in 1872.
A neo-Renaissance building was erected in the early 20th century. It was the first building in the town designed to serve its needs as a museum. There are sculptures of Perseus and Vulcan on the facade of the building.
The museum presents the Stone Age and the Middle Age period in eastern Slovakia, the Košice Gold Treasure, jewellery and numismatic exhibits.
Also on the site of the museum, there is a wooden church from Kožuchovce (Svidník district). The church was founded in 1741 and it was brought to Košice in 1927.