Econazole

Econazole
Systematic (IUPAC) name
	(RS)-1-{2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
Clinical data
AHFS/Drugs.com	monograph
MedlinePlus	a684049
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	27220-47-9
ATC code	D01AC03 G01AF05
PubChem	CID 3198
IUPHAR ligand	2446
DrugBank	APRD00943
ChemSpider	3086
UNII	6Z1Y2V4A7M
KEGG	D03936
ChEBI	CHEBI:4754
ChEMBL	CHEMBL808
Chemical data
Formula	C18H15Cl3N2O
Mol. mass	381.683 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C18H15Cl3N2O/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2 ; Key:LEZWWPYKPKIXLL-UHFFFAOYSA-N ;
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Econazole nitrate is an antifungal medication of the imidazole class.^[1] It is used as a cream under the brand names Spectazole (United States), Ecostatin (Canada), Pevaryl (Western Europe) and Pevisone (the latter consisting of the combination econazole/triamcinolone) to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. It is also sold in Canada under the brand name Ecostatin Vaginal Ovules to treat vaginal thrush. In Asia it is sold under the brand name Endix-G (by Dongkwang, Korea) while in Thailand it's sold as Ecosone by Qualimed. In Taiwan it is sold as VIVICOME CREAM and manufactured by Yong Chang Pharmeceuticals.

[edit] References

^ Thienpont, D; Van Cutsem, J; Van Nueten, JM; Niemegeers, CJ; Marsboom, R (1975). "Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic". Arzneimittel-Forschung 25 (2): 224–30. PMID 1173036.

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