Econazole

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Econazole
Econazole.svg
Systematic (IUPAC) name
(RS)-1-{2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a684049
Legal status
?
Identifiers
CAS number 27220-47-9
ATC code D01AC03 G01AF05
PubChem CID 3198
IUPHAR ligand 2446
DrugBank DB01127
ChemSpider 3086 YesY
UNII 6Z1Y2V4A7M YesY
KEGG D03936 YesY
ChEBI CHEBI:4754 YesY
ChEMBL CHEMBL808 YesY
Chemical data
Formula C18H15Cl3N2O 
Mol. mass 381.683 g/mol
 YesY (what is this?)  (verify)

Econazole (commonly used as the nitrate salt) is an antifungal medication of the imidazole class.[1] It is used as a cream under the brand names Spectazole (United States), Ecostatin (Canada), Pevaryl (Western Europe) and Pevisone (the latter consisting of the combination econazole/triamcinolone) to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. It is also sold in Canada under the brand name Ecostatin as vaginal ovules to treat vaginal thrush. In Asia, it is sold under the brand name Endix-G (by Dongkwang, Korea), while in Thailand it is sold as Ecosone by Qualimed. In Taiwan, it is sold as Vivicome Cream, manufactured by Yong Chang Pharmaceuticals. In Egypt it is sold as a foam spray by ATM. In Bangladesh it is sold under the brand name Ecoderm by Rephco Pharmaceuticals Ltd. The combination of Econazole nitrate with Triamcinolone acetonide is also available under the brand name Ecoderm-TA.[2]

Adverse Effects[edit]

Studies show that approximately three percent of patients treated with econazole nitrate cream reported side effects. The most common symptoms were burning, itching, erythema, and one outbreak of a pruritic rash.[3]

References[edit]

  1. ^ Thienpont, D; Van Cutsem, J; Van Nueten, JM; Niemegeers, CJ; Marsboom, R (1975). "Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic". Arzneimittel-Forschung 25 (2): 224–30. PMID 1173036. 
  2. ^ Product descriptions at REPHCO Pharmaceuticals Limited, Bangladesh. Retrieved June 2012
  3. ^ Perrigo Econazole Nitrate Cream Product Description. 2012.

External links[edit]