She married Grey on 16 November 1601, at St Martin's-in-the-Fields. They had no children, and the Earl died in 1639. Afterwards she is thought to have married the writer, John Selden, who had worked for the Earl. After her death, her collection of medical recipes was published as A Choice Manual, or Rare Secrets in Physick and Chirurgery Collected and Practised by the Right Honourable the Countess of Kent, late deceased. It was an interest she shared with her younger sister, Alethea Howard, Countess of Arundel.
Spiller, Elizabeth. (2008). Seventeenth-century English recipe books: cooking, physic and chirurgery in the works of Elizabeth Talbot Grey and Aletheia Talbot Howard. Burlington, VT: Ashgate Publishing Company. ISBN978-0-7546-51963.