From Wikipedia, the free encyclopedia
Jump to: navigation, search
Combination of
Elvitegravir Integrase inhibitor
Cobicistat Cytochrome P450 inhibitor
Emtricitabine Reverse-transcriptase inhibitor
Tenofovir disoproxil fumarate Reverse-transcriptase inhibitor
Clinical data
Trade names Stribild
AHFS/Drugs.com entry
Pregnancy cat.
Legal status
Routes Oral
ATC code J05AR09
DrugBank http://www.drugbank.ca/drugs/DB00300

Elvitegravir/cobicistat/emtricitabine/tenofovir (brand name Stribild), also known as the Quad pill, is a fixed dose combination drug for the treatment of HIV/AIDS. Elvitegravir, emtricitabine and tenofovir directly suppress viral reproduction. Cobicistat increases the effectiveness of the combination by inhibiting liver enzymes that metabolize the other components. Stribild gained approval by U.S. Food and Drug Administration on August 27, 2012 for use in adult patients starting HIV treatment for the first time as part of the fixed dose combination.