Embryonal rhabdomyosarcoma
From Wikipedia, the free encyclopedia
| Embryonal rhabdomyosarcoma | |
|---|---|
| Classification and external resources | |
| OMIM | 268210 180295 |
| DiseasesDB | 1557 |
Embryonal rhabdomyosarcoma (ERMS) is a rare histological form of cancer of connective tissue wherein the mesenchymally-derived malignant cells resemble the primitive developing skeletal muscle of the embryo. It is the most common soft tissue sarcoma occurring in children.[1]
[edit] Classification
ERMS is the more common of two major subtypes of rhabdomyosarcoma, the other being alveolar rhabdomyosarcoma.
It has been informally classified as a "small round blue cell tumor"[1] because of the characteristic microscopic appearance of its cells after histological staining with hematoxylin and eosin.
[edit] Prognosis and survival
The prognosis for rhabdomyosarcoma has improved greatly in recent decades, with over 70% of victims surviving for five years after diagnosis.[2]
[edit] References
- ^ a b Masola V, Maran C, Tassone E, Zin A, Rosolen A, Onisto M (2009). "Heparanase activity in alveolar and embryonal rhabdomyosarcoma: implications for tumor invasion". BMC Cancer 9: 304. doi:10.1186/1471-2407-9-304. PMC 2743710. PMID 19715595. http://www.biomedcentral.com/1471-2407/9/304.
- ^ Breitfeld PP, Meyer WH (August 2005). "Rhabdomyosarcoma: new windows of opportunity". Oncologist 10 (7): 518–27. doi:10.1634/theoncologist.10-7-518. PMID 16079319. http://theoncologist.alphamedpress.org/cgi/pmidlookup?view=long&pmid=16079319.
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