Emil Herman Grubbe (1 January 1875 — 26 March 1960) was probably the first American to use x-rays in the treatment of cancer. He was born in Chicago, and received his medical training at a homeopathic institute: the Hahnemann Medical College of Chicago. It was there that Grubbe assembled the first x-ray machine in Chicago in 1896, and that same year, used it to treat a woman with recurrent carcinoma of the breast. He assembled the machine and began to use it in treatments less than a year after Wilhelm Röntgen announced his discovery of the x-ray. By 1960, Grubbe had instructed over 7000 other doctors in the medical use of x-rays. In the course of his lifetime, he underwent more than 90 operations for multiple cancers caused by his intense, ongoing exposure to radiation. Honors were bestowed upon Grubbe by numerous institutions, including the American Cancer Society. He was also a fellow of the American College of Physicians. Grubbe left money in his will to the Chicago Radiological Society to fund the Grubbe Memorial Award.
- "Pioneer in X-Ray Therapy". Science (New Series) 125 (3236): 18–19. 4 January 1957. JSTOR 1752791.
- Pendergrass, Eugene P. (Autumn 1965). "Review of The Life and Times of Emil H. Grubbe by Paul C. Hodges". Isis 56 (3): 395. doi:10.1086/350038. JSTOR 228144.
- "Brief Biography of Emil Grubbe". Chicago Radiological Society. Retrieved 8 September 2011.
- "Emil H. Grubbe, M.D., F.A.C.P. (obituary)". British Medical Journal 2 (5198): 609. 20 August 1960. doi:10.1136/bmj.2.5198.609-a. JSTOR 25392632.
- Evans, Titus C. (June 1951). "Review of X-Ray Treatment: Its Origin, Birth, and Early History by Emil Grubbe". Quarterly Review of Biology 26 (2): 223. doi:10.1086/398163. JSTOR 2809298.
- Grubbe, Emil (1949). X-Ray Treatment: Its Origins, Birth, and Early History. St. Paul and Minneapolis, MN: Bruce Publishing Company.
- Hodges, Paul C. (1964). The Life and Times of Emil H. Grubbe. University of Chicago Press.
- Mukherjee, Siddhartha (16 November 2010). The Emperor of All Maladies: A Biography of Cancer. Simon and Schuster. ISBN 978-1-4391-0795-9. Retrieved 6 September 2011.
- "X-Ray Martyr". Time. 3 August 1959.