End organ damage

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End organ or target organ damage usually refers to damage occurring in major organs fed by the circulatory system (heart, kidneys, brain, eyes) which can sustain damage due to uncontrolled hypertension, hypotension, or hypovolemia.

Evidence of hypertensive damage[edit]

In the context of hypertension features looked for, at least in the initial work-up, include:[1]

Evidence of shock (poor end organ perfusion)[edit]

  • Kidney - poor urine output (less than 0/5mL/kg), low GFR
  • Skin - pallor or mottled appearance, capillary refill > 2secs, cool peripheries
  • Brain - orientation to time, person, place, GCS if altered consciousness