The CSIs are called to a crime scene at a brothel in Bryant County where Lorenzo "Happy" Morales, a boxer, is found dead in a swimming pool. He has two puncture wounds in his neck and a contusion on his head, and a broken chair lies by the pool. Grissom mentions that he saw Lorenzo fight Leroy Steele once, a reference to the Season 3 episode Fight Night. Brass questions the girls and they all initially say that Happy was a nice person. He threatens to come down hard if he finds out that they are lying and they immediately pour out their discontentment about Happy's disgusting habits. One girl mentions about Binky, the "whorehouse" owner, and his disapproval of Happy's lifestyle. As the investigation goes on, the team are perplexed as Doc's autopsy reports seem to contradict the available evidence. One of the prostitutes, Dreama "confesses" that she killed Happy after hitting him in self-defense. Later, Brass questions Connor, a bartender, and he too "confesses" to killing Happy when he had shot an arrow at Happy in self-defense. However, test results confirm that Happy had died of anaphylaxis caused by a reaction to shellfish, yet there was no trace of any seafood in Happy's stomach and intestines and at the crime scene. Grissom and his team find themselves in a bizarre situation with a victim who seems to have died under even more bizarre circumstances.