Endocrine disease

From Wikipedia, the free encyclopedia
  (Redirected from Endocrine disorders)
Jump to: navigation, search
Endocrine disease
Classification and external resources
Illu endocrine system.png
Major endocrine glands. (Male left, female on the right.) 1. Pineal gland 2. Pituitary gland 3. Thyroid gland 4. Thymus 5. Adrenal gland 6. Pancreas 7. Ovary 8. Testes
ICD-10 E00-E35
ICD-9 240-259
MeSH D004700

Endocrine diseases are disorders of the endocrine system. The branch of medicine associated with endocrine disorders is known as endocrinology.

Types of endocrine disease[edit]

Broadly speaking, endocrine disorders may be subdivided into three groups:[1]

  1. Endocrine gland hyposecretion (leading to hormone deficiency)
  2. Endocrine gland hypersecretion (leading to hormone excess)
  3. Tumours (benign or malignant) of endocrine glands

Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid stimulating hormone.[2]

List of endocrine diseases[edit]

Adrenal disorders[edit]

Glucose homeostasis disorders[edit]

Thyroid disorders[edit]

Calcium homeostasis disorders and Metabolic bone disease[edit]

Pituitary gland disorders[edit]

Posterior pituitary[edit]

Anterior pituitary[edit]

Sex hormone disorders[edit]

Tumours of the endocrine glands not mentioned elsewhere[edit]

See also separate organs[edit]

Endocrine emergencies[edit]

In endocrinology, medical emergencies include diabetic ketoacidosis, hyperosmolar hyperglycemic state, hypoglycemic coma, acute adrenocortical insufficiency, phaeochromocytoma crisis, hypercalcemic crisis, thyroid storm, myxoedema coma and pituitary apoplexy.[3]

Emergencies arising from decompensated pheochromocytomas or parathyroid adenomas are sometimes referred for emergency resection when aggressive medical therapies fail to control the patient's state, however the surgical risks are significant, especially blood pressure lability and the possibility of cardiovascular collapse after resection (due to a brutal drop in respectively catecholamines and calcium, which must be compensated with gradual normalization).[4][5] It remains debated when emergency surgery is appropriate as opposed to urgent or elective surgery after continued attempts to stabilize the patient, notably in view of newer and more efficient medications and protocols.[6][7][8]

See also[edit]

References[edit]

  1. ^ "Endocrine Disorders". webmd. 
  2. ^ "Diagnosing Hyperthyroidism: Overactivity of the Thyroid Gland". endocrineweb. 
  3. ^ Savage, M W; P Mah; A Weetman; J Newell-Price (1 September 2004). "Endocrine emergencies". Postgraduate Medical Journal 80 (947): 506–515. doi:10.1136/pgmj.2003.013474. 
  4. ^ Brouwers, FM; Eisenhofer, G; Lenders, JW; Pacak, K (December 2006). "Emergencies caused by pheochromocytoma, neuroblastoma, or ganglioneuroma.". Endocrinology and metabolism clinics of North America 35 (4): 699–724, viii. doi:10.1016/j.ecl.2006.09.014. PMID 17127142. 
  5. ^ Tahim, AS; Saunders, J; Sinha, P (2010). "A parathyroid adenoma: benign disease presenting with hyperparathyroid crisis.". Case reports in medicine 2010: 596185. doi:10.1155/2010/596185. PMC 3014839. PMID 21209735. Retrieved 23 February 2013. 
  6. ^ Newell, KA; Prinz, RA; Pickleman, J; Braithwaite, S; Brooks, M; Karson, TH; Glisson, S (August 1988). "Pheochromocytoma multisystem crisis. A surgical emergency.". Archives of surgery (Chicago, Ill. : 1960) 123 (8): 956–9. doi:10.1001/archsurg.1988.01400320042007. PMID 2899426. 
  7. ^ Scholten, A.; Cisco, R. M.; Vriens, M. R.; Cohen, J. K.; Mitmaker, E. J.; Liu, C.; Tyrrell, J. B.; Shen, W. T.; Duh, Q.-Y. (2 January 2013). "Pheochromocytoma Crisis Is Not a Surgical Emergency". Journal of Clinical Endocrinology & Metabolism 98 (2): 581–591. doi:10.1210/jc.2012-3020. PMID 23284003. 
  8. ^ Phitayakorn, R; McHenry, CR (June 2008). "Hyperparathyroid crisis: use of bisphosphonates as a bridge to parathyroidectomy.". Journal of the American College of Surgeons 206 (3): 1106–15. doi:10.1016/j.jamcollsurg.2007.11.010. PMID 18501807. 

External links[edit]