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An Endoribonuclease is a ribonuclease endonuclease. It cleaves either single-stranded or double-stranded RNA, depending on the enzyme. Example includes both single proteins like RNase III, RNase A, RNase T1, and RNase H, and also complexes of proteins with RNA like RNase P and the RNA-induced silencing complex. Further examples include, Endoribonuclease XendoU found in frogs (Xenopus).

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