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Classification and external resources
Endosalpingiosis - cropped 2 - very high mag.jpg
High magnification micrograph of endosalpingiosis, showing the characteristic cystic spaces lined by a simple epithelium with cilia. H&E stain.

In gynecology, endosalpingiosis is a condition in which fallopian tube-like epithelium is found outside of the fallopian tube. It is unknown what causes this condition. It is generally accepted that the condition develops from transformation of coelomic tissue.[1] It is often an incidental finding and is not usually associated with any pathology.


The significance of endosalpingiosis is not settled; medical experts differ on whether the condition itself causes issues or whether it is an asymptomatic finding. Common symptoms include, pelvic pain, infertility, menstrual irregularities and dyspareunia. Further reports suggest chronic back pain as a common issue reported years before diagnosis.[2][3] Experts are unclear as the condition itself is a rare finding and lack of knowledge presents itself as a challenge.


Micrograph showing endosalpingiosis in a lymph node. H&E stain.

Endosalpingiosis is diagnosed by a pathologist on excision (e.g. biopsy).

It is characterized by cysts with tubal-type epithelium (e.g. ciliated epithelium) surrounded by a fibrous stroma. It is not often associated with hemorrhage.

A tubal-type epithelial surrounded by endometrial-type stroma is a variant of endometriosis, not endosalpingiosis.

Endosalpingiosis is occasionally found in lymph nodes, and may be interpreted as an adenocarcinoma metastasis.[4]


As endosalpingiosis, generally, is not considered a pathology, treatment is not always necessary. However the treatment of other problems caused by this condition, such as ovarian cysts, chocolate cysts, fertility, pelvic pain, adhesions, dyspareunia may need to be addressed depending on the case.

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  1. ^ http://www.hindawi.com/journals/criog/2012/329416/
  2. ^ deHoop, TA.; Mira, J.; Thomas, MA. (Oct 1997). "Endosalpingiosis and chronic pelvic pain.". J Reprod Med 42 (10): 613–6. PMID 9350013. 
  3. ^ Heinig, J.; Gottschalk, I.; Cirkel, U.; Diallo, R. (Jun 2002). "Endosalpingiosis-an underestimated cause of chronic pelvic pain or an accidental finding? A retrospective study of 16 cases.". Eur J Obstet Gynecol Reprod Biol 103 (1): 75–8. PMID 12039470. 
  4. ^ Corben, AD.; Nehhozina, T.; Garg, K.; Vallejo, CE.; Brogi, E. (Aug 2010). "Endosalpingiosis in axillary lymph nodes: a possible pitfall in the staging of patients with breast carcinoma.". Am J Surg Pathol 34 (8): 1211–6. doi:10.1097/PAS.0b013e3181e5e03e. PMID 20631604. 

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