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An enema (//; plural enemata or enemas) is the procedure of introducing liquids into the rectum and colon via the anus. The increasing volume of the liquid causes rapid expansion of the lower intestinal tract, often resulting in very uncomfortable bloating, cramping, powerful peristalsis, a feeling of extreme urgency and complete evacuation of the lower intestinal tract. An enema has the advantage over any laxative in its speed and certainty of action, and some people prefer it for this reason.
Enemas can be carried out as treatment for medical conditions, such as constipation and encopresis, and as part of some alternative health therapies. They are also used to administer certain medical or recreational drugs. Enemas have been used for rehydration therapy (proctoclysis) in patients for whom intravenous therapy is not applicable.
Enema comes from Greek ἔνεμα (énema), from ἐνίημι (eníēmi), "(I) inject".
Clyster (/ˈklɪstə(r)/), also spelled glister in the 17th century, comes from Greek κλυστήρ (klystḗr), from κλύζω (klýzo), "(I) wash". It is an archaic word for enema, more particularly for enemas administered using a clyster syringe – that is, a syringe with a rectal nozzle and a plunger rather than a bulb. Clyster syringes were used from the 17th century (or before) to the 19th century, when they were largely replaced by enema bulb syringes, bocks, and bags.
The patient was placed in an appropriate position (kneeling, with the buttocks raised, or lying on the side); a servant or apothecary would then insert the nozzle into the anus and depress the plunger, resulting in the liquid remedy (generally, water, but also some preparations) being injected into the colon.
Because of the embarrassment a woman might feel when showing her buttocks (and possibly her genitals, depending on the position) to a male apothecary, some contraptions were invented that blocked all from the apothecary's view except for the anal area. Another invention was syringes equipped with a special bent nozzle, which enabled self-administration, thereby eliminating the embarrassment.
Clysters were administered for symptoms of constipation and, with more questionable effectiveness, stomach aches and other illnesses. In his early-modern treatise, The Diseases of Women with Child, François Mauriceau records that both midwives and man-midwives commonly administered clysters to labouring mothers just prior to their delivery.
In Roper's biography of his father-in-law Sir Thomas More, he tells of Thomas More's eldest daughter falling sick of the sweating sickness. She could not be awakened by doctors. After praying, it came to Thomas More:
There straightway it came into his mind that a clyster would be the one way to help her, which when he told the physicians, they at once confessed that if there were any hope of health, it was the very best help indeed, much marveling among themselves that they had not afore remembered it.
Clysters were a favourite medical treatment in the bourgeoisie and nobility of the Western world up to the 19th century. As medical knowledge was fairly limited at the time, purgative clysters were used for a wide variety of ailments, the foremost of which were stomach aches and constipation. Molière, in several of his plays, introduces characters of incompetent physicians and apothecaries fond of prescribing this remedy, also discussed by Argan, the hypochondriac patient of Le Malade Imaginaire. More generally, clysters were a theme in the burlesque comedies of that time. According to Claude de Rouvroy, duc de Saint-Simon, clysters were so popular at the court of King Louis XIV of France that the duchess of Burgundy had her servant give her a clyster in front of the King (her modesty being preserved by an adequate posture) before going to the comedy. However, he also mentions the astonishment of the King and Mme de Maintenon that she should take it before them.
Medical usage 
The main medical usages of enemas are:
- As a bowel stimulant, not unlike a laxative – the main difference being that laxatives are commonly thought of as orally administered while enemas are administered directly into the rectum, and thereafter, into the colon. When the enema injection into the rectum is complete, and after a set "holding time", the patient expels feces along with the enema in the bedpan or toilet.
- Enemas may also be used to relieve constipation and fecal impaction, although in the U.S.A. and some other parts of the world, their use has been replaced in most professional health-care settings by oral laxatives and laxative suppositories. In-home use of enemas for constipation and alternative health purposes is somewhat harder to measure.
- Bowel stimulating enemas usually consist of water, which works primarily as a mechanical stimulant, or they may be made up of water with baking soda (sodium bicarbonate) or water with a mild hand soap dissolved in it. Buffered sodium phosphate solution draws additional water from the bloodstream into the colon to increase the effectiveness of the enema, but can be rather irritating to the colon, causing intense cramping or "griping." Mineral oil functions as a lubricant and stool softener, but often has the side effect of sporadic seepage from the patient's anus which can soil undergarments for up to 24 hours. Glycerol is a specific bowel mucosa irritant and when introduced in very dilute solution serves to induce peristalsis.
- Other types of enema solutions are also used, including equal parts of milk and molasses heated together to slightly above normal body temperature. In the past, castile soap was a common additive in an enema, but it has largely fallen out of use because of its irritating action in the rectum and because of the risk of chemical colitis as well as the ready availability of other enema preparations that are perhaps more effective than soap in stimulating a bowel movement. At the opposite end of the spectrum, an isotonic saline solution is least irritating to the rectum and colon, having a neutral concentration gradient. This neither draws electrolytes from the body – as can happen with plain water – nor draws water into the colon, as will occur with phosphates. Thus, a salt water solution can be used when a longer period of retention is desired, such as to soften an impaction.
- Cleansing the lower bowel prior to a surgical procedure such as sigmoidoscopy or colonoscopy. Because of speed and supposed convenience, enemas used for this purpose are commonly the more costly, sodium phosphate variety – often called a disposable enema. A more pleasant experience preparing for testing procedures can usually be obtained with gently administered baking soda enemas; cleansing the lower bowel for colonoscopy and other bowel studies can be effectively achieved with water-based, or water with baking soda, enema administration.
- The administration of substances into the bloodstream. This may be done in situations where it is undesirable or impossible to deliver a medication by mouth, such as antiemetics given to reduce nausea (though not many antiemetics are delivered by enema). Additionally, several anti-angiogenic agents, which work better without digestion, can be safely administered via a gentle enema. Medicines for cancer, for arthritis, and for age-related macular degeneration are often given via enema in order to avoid the normally-functioning digestive tract. Interestingly, some water-based enemas are also used as a relieving agent for irritable bowel syndrome, using cayenne pepper to squelch irritation in the colon and rectal area. Finally, an enema may also be used for hydration purposes. See also route of administration.
- Emergency blood expansion. Emergency pre-hospital treatment of haemorrhage requires immediate fluid replacement therapy. In mass casualty, remote or rural settings, the lack of sterile fluids, intravenous equipment or the knowledge to use them might limit the treatment options available. In such situations proctoclysis remains an easy, safe and effective way to provide fluid replacement. It does not require sterile fluids, special equipment or complex training, and it is useful when alternative routes are not readily available.
- The topical administration of medications into the rectum, such as corticosteroids and mesalazine used in the treatment of inflammatory bowel disease. Administration by enema avoids having the medication pass through the entire gastrointestinal tract, therefore simplifying the delivery of the medication to the affected area and limiting the amount that is absorbed into the bloodstream.
- General anesthetic agents for surgical purposes are sometimes administered by way of an enema. Occasionally, anesthetic agents are used rectally to reduce medically induced vomiting during and after surgical procedures, in an attempt to avoid aspiration of stomach contents.
- A barium enema is used as a contrast substance in the radiological imaging of the bowel. The enema may contain barium sulfate powder, or a water-soluble contrast agent. Barium enemas are sometimes the only practical way to "view" the colon in a relatively safe manner. Following barium enema administration, patients often find that flushing the remaining barium with additional water, baking soda, or saline enemas helps restore normal colon activity without complications of constipation from the administration of the barium sulfate.
- Rectal corticosteroid enemas are sometimes used to treat mild or moderate ulcerative colitis. They also may be used along with systemic (oral or injection) corticosteroids or other medicines to treat severe disease or mild to moderate disease that has spread too far to be treated effectively by medicine inserted into the rectum alone.
In certain countries, such as the United States, customary enema usage went well into the 20th century; it was thought a good idea to cleanse the bowel in case of fever; also, pregnant women were given enemas prior to labor, supposedly to reduce the risk of feces being passed during contractions. Under some controversial discussion, pre-delivery enemas were also given to women to speed delivery by inducing contractions. This latter usage has since been largely abandoned, because obstetricians now commonly give pitocin to induce labor and because women generally found the procedure unpleasant.
Home usage 
Many self-given enemas used at home are the packaged, disposable, sodium phosphate solutions in single-use bottles sold under a variety of brand names, or in generic formats. These units come with a lubricated nozzle attached to the top of the container. Some enemas are administered using so-called disposable bags connected to disposable tubing (despite the names, such units can commonly be used for many months or years without significant deterioration).
Patients who want easier, more gently accepted enemas often purchase combination enema syringes which are commonly referred to as "closed top" syringes, and which can also be used as old-fashioned hot water bottles, so as to relieve aches and pains via gentle heat administrations to parts of the body.
In Asian countries, particularly in Japan, commercially available disposable enemas typically contain glycerin (at concentrations varying from 30-50%) or sodium chloride. They are not lubricated and the amount of liquid contained in them may vary, although most contain about 20-40ml of diluted glycerin.
In medical or hospital environments, reusable enema equipment is now rare because of the expense of disinfecting a water-based solution. For a single-patient stay of short duration, an inexpensive disposable enema bag can be used for several days or weeks, using a simple rinse out procedure after each enema administration. The difficulty comes from the longer time period (and expense) required of nursing aides to give a gentle, water-based enema to a patient, as compared to the very few minutes it takes the same nursing aide to give the more irritating, cold, packaged sodium phosphate unit.
For home use, disposable enema bottle units are common, but reusable rubber or vinyl bags or enema bulbs may also be used. In former times, enemas were infrequently administered using clyster syringes. If such commercially available items are not at hand, ordinary water bottles are sometimes used.
Alternative medicine 
The term "colonic irrigation" is commonly used in gastroenterology to refer to the practice of introducing water through a colostomy or a surgically constructed conduit as a treatment for constipation. The Food and Drug Administration has ruled that colonic irrigation equipment is not approved for sale for the purpose of general well-being and has taken action against many distributors of this equipment, including a Warning Letter. The use of enemas for reasons other than the relief of constipation is currently regulated in some parts of the United States while practitioners in other states may go through a voluntary certification process.
Colon cleansing 
The same term is also used in alternative medicine where it may involve the use of substances mixed with water in order to detoxify the body. Practitioners believe the accumulation of fecal matter in the large intestine leads to ill health. This resurrects the old medical concept of autointoxication which was orthodox doctrine up to the end of the 19th century but which has now been discredited.
Coffee enemas 
Rectal drug administration 
Enemas have also been used for ritual rectal drug administration such as balché, alcohol, tobacco, peyote, and other hallucinogenic drugs and entheogens, most notably by the Maya and also some other American Indian tribes. Some tribes continue the practice in the present day.
People who wish to become intoxicated faster have also been known to use an alcohol enema as a method to instill alcohol into the bloodstream, absorbed through the membranes of the colon. However, great care must be taken as to the amount of alcohol used. Only a small amount is needed as the intestine absorbs the alcohol more quickly than the stomach. Deaths have resulted due to alcohol poisoning via enema.
Recreational usage 
Enemas may be used as part of BDSM activities, or as a regular sexual activity for an individual or between partners. Enemas can be pleasurable to either sex, and in males, enemas can stimulate the prostate gland. Unexpected erections are common in medical settings, even if the person would otherwise consider it an unpleasant procedure.
An enema may also be used prior to anal sex or anilingus in order to enhance the sensation of intercourse, or to remove feces prior to sex, possibly reducing bacterial transmission and risk of infection, or just to reduce the possibility of fecal material or detritus from sexual activity adhering to the genitals or sex toys used during the subsequent activity. Enemas used for anal sex should not be used consistently and enema bottle contents should be removed and replaced with simple luke-warm water. Continual usage of enema solution may be harmful for the anal cavity.
Punitive usage 
Antagonistic factions in unstable nations have often forcibly applied enemas as a means of punishment. In the vastly influential Latin American text Facundo, or Civilization and Barbarism, for example, Domingo Faustino Sarmiento describes the use of pepper and turpentine enemas by police forces as a way of discouraging political dissent in post-independence Argentina.
Improper administration of an enema may cause electrolyte imbalance (with repeated enemas) or ruptures to the bowel or rectal tissues resulting in internal bleeding. However, these occurrences are rare in healthy, sober adults. Internal bleeding or rupture may leave the individual exposed to infections from intestinal bacteria. Blood resulting from tears in the colon may not always be visible, but can be distinguished if the feces are unusually dark or have a red hue. If intestinal rupture is suspected, medical assistance should be obtained immediately.
The enema tube and solution may stimulate the vagus nerve, which may trigger an arrhythmia such as bradycardia. Enemas should not be used if there is an undiagnosed abdominal pain since the peristalsis of the bowel can cause an inflamed appendix to rupture.
There are arguments both for and against colonic irrigation in people with diverticulitis, ulcerative colitis, Crohn's disease, severe or internal hemorrhoids or tumors in the rectum or colon, and its usage is not recommended soon after bowel surgery (unless directed by one's health care provider). Regular treatments should be avoided by people with heart disease or renal failure. Colonics are inappropriate for people with bowel, rectal or anal pathologies where the pathology contributes to the risk of bowel perforation.
A recent case series of 11 patients with five deaths illustrated the danger of phosphate enemas in high-risk patients.
See also 
|Wikimedia Commons has media related to: Enemas|
- Bruera, E; Pruvost, M; Schoeller, T; Montegjo, G; Watanabe, S (April 1998). "Proctoclysis for Hydration of Terminally Ill Cancer Patients". Jour Pain Symptom Management 15 (4): pp 216–9. doi:10.1016/S0885-3924(97)00367-9.
- Locke GR, Pemberton JH, Phillips SF (2000). "AGA technical review on constipation". Gastroenterology 119 (6): 1766–78. doi:10.1053/gast.2000.20392. PMID 11113099.
- "Subpart F--Therapeutic Devices Sec. 876.5220 Colonic irrigation system". Code of Federal Regulations, Title 21 Food and Drugs, Subchapter H -- Medical Devices, Part 876 -- Gatroenterology-Urology Devices. FDA. 2007-04-01.
- Department of Health and Human Services (1999-07-21). "Warning letter to Dotolo Research Corp" (reprint by Casewatch). FDA. Retrieved 2007-12-31.
- Whorton J (2000). "Civilisation and the colon: constipation as the "disease of diseases"". BMJ 321 (7276): 1586–9. doi:10.1136/bmj.321.7276.1586. PMC 1119264. PMID 11124189.
- E.M.D. Ernst (June 1997). "Colonic Irrigation and the Theory of Autointoxication". Journal of Clinical Gastroenterology 24 (4): 196–198. doi:10.1097/00004836-199706000-00002. PMID 9252839
- Kaiser (1985). "The Case Against Colonic Irrigation". California Morbidity (38).
- Chen TS, Chen PS (1989). "Intestinal autointoxication: a medical leitmotif". Journal of Clinical Gastroenterology 11 (4): 434–41. doi:10.1097/00004836-198908000-00017. PMID 2668399.
- "The Gerson Institute — Alternative Cancer Treatment".
- Hills, Ben. "Fake healers. Why Australia’s $1 billion-a-year alternative medicine industry is ineffective and out of control.". Medical Mayhem. Retrieved 2008-03-06. "Kefford is particularly concerned about cancer patients persuaded to undergo the much-hyped US Gerson diet program, which involves the use of ground coffee enemas which can cause colitis (inflammation of the bowel), fluid and electrolyte imbalances, and in some cases septicaemia. The US FDA has warned against this regime, which is known to have caused at least three deaths."
- de Boer AG, Moolenaar F, de Leede LG, Breimer DD (1982). "Rectal drug administration: clinical pharmacokinetic considerations". Clin Pharmacokinet 7 (4): 285–311. PMID 6126289.
- Diamond, Jared M. (1992). The Third Chimpanzee: The Evolution and Future of the Human Animal (P.S.). New York, N.Y: Harper Perennial. p. 432. ISBN 0-06-084550-3.; pp. 201
- "The Enema Within". Darwin Awards. 2008. Retrieved 2008-01-11.
- "Ribbons and Rituals". In Problems in Modern Latin American History. Ed. Chasteen and Wood. Oxford, UK: Scholarly Resources, 2005. p. 97
- Martelli, ME. Encyclopedia of Nursing and Allied Health ([dead link] – Scholar search). FindArticles. Archived from the original on January 23, 2008. Retrieved 2008-01-11
- "Colon Hydrotherapy". Aetna IntelliHealth. 2005-07-01. Retrieved 2007-04-23.
- Eliakim, Rami; Karmeli, Fanny; Rachmilewitz, Danny; Cohen, Petricia; Zimran, Ari (2004-01-04). "Ozone Enema: A Model of Microscopic Colitis in Rats". Digestive Diseases and Sciences 46 (11): 2515–20. doi:10.1023/A:1012348525208. PMID 11713963.
- Ori, Yaacov; Rozen-Zvi, B; Chagnac, A; Herman, M; Zingerman, B; Atar, E; Gafter, U; Korzets, A (2012). "Fatalities and Severe Metabolic Disorders Associated With the Use of Sodium Phosphate Enemas". Archives of Internal Medicine 172 (3): 263–5. doi:10.1001/archinternmed.2011.694. PMID 22332159.