Enkephalinase inhibitor

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An enkephalinase inhibitor is a type of enzyme inhibitor which inhibits one or more members of the enkephalinase class of enzymes that break down the endogenous enkephalin opioid peptides. Examples include racecadotril, ubenimex, RB-101, and D-phenylalanine, as well as the endogenous opioid peptides opiorphin and spinorphin.[1] Analgesic, anticraving, antidepressant, anxiolytic, and antidiarrheal effects are common properties of enkephalinase inhibitors.[1]

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  1. ^ a b Thanawala V, Kadam VJ, Ghosh R (October 2008). "Enkephalinase inhibitors: potential agents for the management of pain". Current Drug Targets 9 (10): 887–94. doi:10.2174/138945008785909356. PMID 18855623.