Enoximone

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Enoximone
Enoximone.svg
Systematic (IUPAC) name
4-methyl-5-{[4-(methylsulfanyl)phenyl]carbonyl}-2,3-dihydro-1H-imidazol-2-one
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
Routes Intravenous
Pharmacokinetic data
Bioavailability 50% (oral)
Protein binding 85%
Metabolism Hepatic oxidation
Half-life 4 to 10 hours
Excretion Renal (60 to 70%)
Identifiers
CAS number 77671-31-9 YesY
ATC code C01CE03
PubChem CID 53708
DrugBank DB04880
ChemSpider 48492 YesY
UNII C7Z4ITI7L7 YesY
KEGG D04004 YesY
ChEMBL CHEMBL249856 YesY
Chemical data
Formula C12H12N2O2S 
Mol. mass 248.302 g/mol
 YesY (what is this?)  (verify)

Enoximone (INN, trade name Perfan) is an imidazole phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure and is selective for phosphodiesterase 3.[1]

References[edit]

  1. ^ Boldt J, Suttner S (September 2007). "Combined use of ultra-short acting beta-blocker esmolol and intravenous phosphodiesterase 3 inhibitor enoximone". Expert Opin Pharmacother 8 (13): 2135–47. doi:10.1517/14656566.8.13.2135. PMID 17714066.