It is found in the mouth between the gingival pockets and near the base of the teeth. Entamoeba gingivalis is found in 95% of people with gum disease and in 50% of people with healthy gums. The cyst formation is not present, therefore transmission is direct from one person to another by kissing, or by sharing eating utensils. Only the trophozoites are formed and the size is usually 20 micrometer to 150 micrometer in diameter. Entamoeba gingivalis have pseudopodia that allow them to move quickly and phagocytise nucleus of polynuclear neutrophil by exonucleophagy in periodontal disease. Their spheroid nucleus is 2 micrometer to 4 micrometer in diameter and contains a small central endosome. There are numerous food vacuoles and contain cellular debris, blood cells and bacteria.
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