Enterococcus faecium

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Not to be confused with Enterococcus faecalis.
Enterococcus faecium
Scientific classification
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Enterococcaceae
Genus: Enterococcus
Species: E. faecium
Binomial name
Enterococcus faecium
(Orla-Jensen 1919)
Schleifer & Kilpper-Bälz 1984

Enterococcus faecium is a Gram-positive, alpha-hemolytic or nonhemolytic bacterium in the genus Enterococcus.[1] It can be commensal (innocuous, coexisting organism) in the human intestine, but it may also be pathogenic, causing diseases such as neonatal meningitis or endocarditis.

Vancomycin-resistant E. faecium is often referred to as VRE.[2]

Some strains of E. faecium are used as probiotics in both animals,[3] and humans.[4]

Genome sequences[edit]

Genomes listed below are from the Integrated Microbial Genomes website.

The 22 sequenced Enterococcus faecium genomes

Strain ST CC17 Country Year
1,231,408 582 Yes NA NA
1,231,501 52 No NA NA
Com15 583 No USA (MA) 2006
1,141,733 327 No NA NA
1,230,933 18 Yes NA NA
1,231,410 17 Yes NA NA
1,231,502 203 Yes NA NA
Com12 107 No USA (MA) 2006

Treatment[edit]

Linezolid or daptomycin is used to treat VRE infections. The streptogramins, such as quinupristin/dalfopristin, may also be used for VREs. VRE can be successfully treated with sultamicillin.[5]

References[edit]

  1. ^ Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. pp. 294–5. ISBN 0-8385-8529-9. 
  2. ^ Mascini EM, Troelstra A, Beitsma M, et al. (March 2006). "Genotyping and preemptive isolation to control an outbreak of vancomycin-resistant Enterococcus faecium". Clin. Infect. Dis. 42 (6): 739–46. doi:10.1086/500322?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dncbi.nlm.nih.gov. PMID 16477546. 
  3. ^ http://www.purinaveterinarydiets.com/Product/FortiFloraCatNutritionalSupplements.aspx
  4. ^ Sisson, G.; Ayis, S.; Sherwood, RA.; Bjarnason, I. (Jul 2014). "Randomised clinical trial: A liquid multi-strain probiotic vs. placebo in the irritable bowel syndrome--a 12 week double-blind study.". Aliment Pharmacol Ther 40 (1): 51–62. doi:10.1111/apt.12787. PMID 24815298. 
  5. ^ Chewning JH, et al. "Vancomycin resistant Enterococcus faecium bacteremia successfully treated with high dose ampicillin sulbactam in a pediatric patient after hematopoietic stem cell transplantation". J. Pediatr. Hematol. Oncol.2011rfr_id=10.1097/MPH.0b013e31820db7eb. 

Further reading[edit]

Sadowy, E; Luczkiewicz, A (14 March 2014). "Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.". BMC microbiology 14: 66. doi:10.1186/1471-2180-14-66. PMID 24629030. Retrieved 12 November 2014.