Enteroenteric circulation

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Enteroenteric circulation is the secretion back into the intestines of substances previously taken up from it. It occurs when there is a negative relative concentration of substance in the intestines, making it passively diffuse from the mesenteric circulation into the intestinal lumen and is trapped.[1]

Examples of toxins that exhibit enteroenteric circulation include theophylline, phenobarbital, and phenytoin.[1] Administration of activated charcoal inhibits the enteroenteric circulation of such substances, and is therefore useful in overdose or intoxication.[2]

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References[edit]

  1. ^ a b The CNYPCC Toxicology Letter Vol. VI No. 2. Central New York Regional Poison Control Center. April, 2001
  2. ^ medscape.com > Use of Activated Charcoal in Drug Overdose. By Desiree Lie, MD, MSEd. Posted: 25 March 2004