Eosinophilia
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| Eosinophilia | |
| Classification and external resources | |
| ICD-10 | D72.1 |
|---|---|
| ICD-9 | 288.3 |
| DiseasesDB | 4328 |
| eMedicine | med/685 |
| MeSH | D004802 |
Eosinophilia is the state of having a high concentration of eosinophils (eosinophil granulocytes) in the blood. The normal concentration is between 0 and 0.5 x 109 eosinophils per litre of blood. Eosinophilia can be reactive (in response to other stimuli such as allergy or infection) or non reactive.
The release of interleukin 5 by T cells, mast cells and macrophages stimulates the production of eosinophils.
[edit] Causes
Diseases that feature eosinophilia:
- Hypereosinophilic syndrome
- Parasitic infections (intestinal helminthiasis)
- Allergic disorders (including eosinophilic esophagitis)
- Some drug reactions, e.g. DRESS syndrome
- Cholesterol embolization
- Churg-Strauss syndrome
- Some forms of chronic myeloid leukaemia
- Hodgkin's lymphoma
- Gleich's syndrome
- Addison's disease
- Clonorchis sinensis, a type of flatworm
- Eosinophilia-myalgia syndrome caused by contaminated tryptophan supplements
- Job's Syndrome caused by increased levels of Immunoglobulin E
- A form of Colitis, eosinophilic colitis
A useful mnemonic for remembering causes of eosinophilia is NAACCP: Neoplasia, Addison Disease, Allergy/Asthma, Collagen Vascular diseases, Cholesterol emboli, and parasites.
[edit] References
[edit] See also
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