Ephraim Engleman (born March 24, 1911) is an American rheumatologist and a clinical professor of Medicine at the University of California, San Francisco. He has had major national and international impact on rheumatology over the past six decades, and he has written more than one hundred scientific and medical papers.
He is currently the Director of the Rosalind Russell Medical Research Center for Arthritis at UCSF, which he founded in 1979. Still active at the age of 102, he is the longest tenured professor of UCSF as of December 30, 2013[update].
As of January 2013, he is believed to be the last surviving member of Stanford University's Class of 1933.