Escaline

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Escaline
Escaline2DACS.svg
Escaline-3d-sticks.png
Names
IUPAC name
2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine
Other names
3,5-Dimethoxy-4-ethoxy-phenethylamine
2-(4-Ethoxy-3,5-dimethoxyphenyl)ethanamine
Identifiers
39201-82-6 YesY
ChEMBL ChEMBL319415 YesY
ChemSpider 35053 YesY
Jmol-3D images Image
Image
PubChem 38240
Properties
C12H19NO3
Molar mass 225.28 g/mol
Melting point 165 to 166 °C (329 to 331 °F; 438 to 439 K) (hydrochloride)
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Escaline or 3,5-methoxy-4-ethoxyphenethylamine is a psychedelic drug and entheogen of the phenethylamine class of compounds. Escaline was first synthesized and reported in the scientific literature by Benington, et al., in 1954, but was later re-examined in the laboratory of David E. Nichols, who prepared a series of mescaline analogues that included escaline, proscaline, and isoproscaline. The effects of this and related mescaline analogues in humans were first described by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin lists the dosage range as 40 to 60 mg, consumed orally. The duration of action was stated to be 8 – 12 hours.

Escaline is the phenethylamine analog of 3C-E and the 4-ethoxy analog of mescaline.

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