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Systematic (IUPAC) name
Clinical data
Legal status
CAS number 29331-92-8
ATC code None
PubChem CID 114709
ChemSpider 102704
Chemical data
Formula C15H14N2O2 
Mol. mass 254.28 g/mol
Physical data
Spec. rot racemic

Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine.[1] It is an active metabolite of oxcarbazepine.[1][2] In addition, an isomer of licarbazepine, eslicarbazepine ((S)-(+)-licarbazepine), is an active metabolite of eslicarbazepine acetate.[1][2] Oxcarbazepine and eslicarbazepine acetate are inactive on their own, and behave instead as prodrugs to licarbazepine and eslicarbazepine, respectively, to produce their therapeutic effects.[1][2]


  1. ^ a b c d Singh RP, Asconapé JJ (2011). "A review of eslicarbazepine acetate for the adjunctive treatment of partial-onset epilepsy". J Cent Nerv Syst Dis 3: 179–87. doi:10.4137/JCNSD.S4888. PMC 3663619. PMID 23861647. 
  2. ^ a b c Bialer M, Soares-da-Silva P (June 2012). "Pharmacokinetics and drug interactions of eslicarbazepine acetate". Epilepsia 53 (6): 935–46. doi:10.1111/j.1528-1167.2012.03519.x. PMID 22612290.