This article may be expanded with text translated from the corresponding article in the Japanese Wikipedia. (February 2009)
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Mami Sakura used to be a normal junior high school student, but she happened to acquire supernatural powers. Using her powers and with the help of her best friend, Mr. Takahata, she solves mysterious occurrences. When she senses someone needs help, she uses the "Teleportation Gun" and transports herself there. She then saves the world in trouble with her psychic powers, such as telekinesis and telepathy.
The chief character. A student of Tobita Junior High School in "the Sama hill", in the suburbs of Tokyo. Her powers are awakened by an unexpected coincidence and she uses the power for acts of kindness afterward. She is bright, but careless and rather meddlesome. Mami isn't very good at studying or housework, especially cooking, which becomes a recurring joke throughout the series. Her father is an artist, and Mami usually poses as nude model for his painting. She was going to reveal her supernatural power to her father, but her friend Kazuo told her that her French ancestors were hunted as witches, and refrains from telling him. She is sometimes called "Mami duke" by her father. Mami has a red hair. She wears a white shirt with a sailor neckerchief, a light blue scarf, blue skirt, white socks and black shoes. When Mami prepared to fly in the sky every night, she wears a white shirt with short sleeves, blue dress, white socks and black shoes. Mami's main power is telekinesis. She also possesses a levitation ability (she can float not only herself but several objects at the same time), telepathy and teleportation, although, she often collides with objects and other people. Takahata created a teleportation gun, so that Mami can control her teleportation.
Kazuo Takahata(高畑和夫,Takahata Kazuo?) (voiced by Hiroyuki Shibamoto)
A student of Tobita Junior High School and Mami's best friend. He originally thought Mami's supernatural powers are his, which upset him greatly when he found the truth but later supports Mami in developing her powers. He is a real genius, helping Mami understand her powers and develop them. Although he really likes amateur baseball, he is awful at it, which make Mami sometimes secretly interfere to help his team. He often comes up with alibis for Mami whenever she gets in trouble with her parents. He has a good understanding of Mami, and often supports her.
A dog which looks more like a raccoon dog or fox, and Mami's pet. He loves fried bean curd, and often cries "Fuyanfuyan". Mary, the neighbor's dog, likes him. For a while, it seemed that he understood human words. He dislikes being mistaken as a fox/raccoon. Originally he hates Kazuo because he often accidentally sing songs about raccoon dogs but later becomes friend when Kazuo saved Mami from a collapsed tunnel.
Mami's father and a painter. He often holds private exhibitions (but the pictures don't sell very well) and also works as art lecturer in a municipal senior high school. He is a laid back, clumsy person who enjoys pickled radish and smoking pipe. His grandfather married a French painter, whose lineage is believed to be the source of Mami's powers. He made an evacuation of schoolchildren in Yamanashi[disambiguation needed] during the war. Because his father was affiliated with Europe and America, he was often bullied in his youth. He calls his daughter "Mami-kō" (Mami duke). He has a younger brother named Hyakuro, and Ichiro, an older brother in the country.
Mami's classmate and a baseball friend of Takahata. He seems to be Yukiko's boyfriend. A person with strong sense of justice, he is a member to the newspaper club, though rather unreliable, but does not yield to threats from delinquents.
Vice Director of the Tobita movie club. He was engaged in film photography when he spotted manipulation had been added to the picture (by Mami). He began to believe that Mami was an esper, and started following her around. His father is a director of a first-class business company.