Ethacizine

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Ethacizine
Ethacizine.svg
Systematic (IUPAC) name
ethyl N-[10-[3-(diethylamino)propanoyl]phenothiazin-2-yl]carbamate
Clinical data
Trade names Ethacizin
AHFS/Drugs.com International Drug Names
Legal status
Pharmacokinetic data
Bioavailability ~40% (oral)[1]
Protein binding 90%
Metabolism Extensive hepatic
Half-life 2.5 hours
Identifiers
CAS number 33414-33-4 YesY
ATC code C01BC09
PubChem CID 107841
ChemSpider 96982 YesY
UNII FE5SPV1Z6G YesY
Chemical data
Formula C22H27N3O3S 
Mol. mass 413.54 g/mol

Ethacizine (ethacyzine) is a class Ic antiarrhythmic agent, related to moracizine. It is used in Russia and some other CIS countries for the treatment of severe and/or refractory ventricular and supraventricular arrhythmias, especially those accompanied by organic heart disease. It is also indicated as a treatment of refractory tachycardia associated with Wolff–Parkinson–White syndrome.[1]

It is manufactured under the brand name Ethacizin (Этацизин) by Olainfarm.[2]

References[edit]

  1. ^ a b "Этацизин (Ethacyzin) Prescribing Information. VIDAL Drug Compendium" (in Russian). Retrieved 5 February 2014. 
  2. ^ "Этацизин—4DOKTOR.RU Drug Information Handbook" (in Russian). Retrieved 5 February 2014.