Ethoxyquin

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Ethoxyquin[1]
Ethoxyquin
Identifiers
CAS number 91-53-2 YesY
PubChem 3293
ChemSpider 3177 YesY
UNII 9T1410R4OR YesY
ChEBI CHEBI:77323 N
ChEMBL CHEMBL172064 YesY
Jmol-3D images Image 1
Properties
Molecular formula C14H19NO
Molar mass 217.31 g mol−1
Melting point < 25 °C
Boiling point 123–125 °C at 2 mmHg
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Ethoxyquin is a quinoline-based antioxidant used as a food preservative (E324) and a pesticide (under commercial names such as "Stop-Scald"). It is commonly used as a preservative in pet foods to prevent the rancidification of fats. Ethoxyquin is also commonly used in spices to prevent color loss due to oxidation of the natural carotenoid pigments.[2]

There has been some speculation that ethoxyquin in pet foods might be responsible for multiple health problems. To date, the U.S. Food and Drug Administration (FDA) has only found a verifiable connection between ethoxyquin and buildup of protoporphyrin IX in the liver, as well as elevations in liver-related enzymes in some animals, but there are no known health consequences from these effects.[3] In 1997, the Center for Veterinary Medicine has asked pet food manufacturers to voluntarily limit ethoxyquin levels to 75 ppm until further evidence is reported.[3] However, most pet foods that contain ethoxyquin have never exceeded this amount.[3]

Ethoxyquin has been shown to be slightly toxic to fish.[4]

Ethoxyquin is not permitted for use in Australian foods nor is it approved for use within in the European Union.[5] It is an approved additive in the United States.

The Environmental Protection Agency has concluded that any cancer risk associated with the use of ethoxyquin "does not exceed the Agency's level of concern".[2]

References[edit]

  1. ^ Merck Index, 11th Edition, 3710
  2. ^ a b R.E.D. FACTS Ethoxyquin. United States Environmental Protection Agency. November 2004. EPA-738-F-04-006. 
  3. ^ a b c Pet Food Labels, U.S. Food and Drug Administration
  4. ^ Ethoxyquin at the PAN pesticide database
  5. ^ http://noshly.com/additive/324/antioxidant/324/