Eticyclidine

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Eticyclidine
Eticyclidine.svg
Systematic (IUPAC) name
N-ethyl-1-phenylcyclohexylamine
Clinical data
Legal status Prohibited (S9) (AU) Schedule I / Class A
Identifiers
CAS number 2201-15-2 YesY
ATC code None
PubChem CID 16622
ChemSpider 15759 YesY
UNII O8I1LL6A89 YesY
ChEMBL CHEMBL279924 YesY
Chemical data
Formula C14H21N 
Mol. mass 203.323 g/mol
 YesY (what is this?)  (verify)

Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400,[1] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties.[2] PCE is slightly more potent than PCP and has similar effects, but its unpleasant taste and tendency to cause nausea made it less accepted by users.[3] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known.

See also[edit]

References[edit]

  1. ^ LEVY L, CAMERON DE, AITKEN RC (March 1960). "Observation on two psychotomimetic drugs of piperidine derivation--CI 395 (sernyl) and CI 400". The American Journal of Psychiatry 116: 843–4. PMID 14416411. 
  2. ^ Kalir A, Edery H, Pelah Z, Balderman D, Porath G. 1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity. Journal of Medicinal Chemistry. 1969. 12(3):473-477
  3. ^ Structure Activity of PCP analogs