Etoxeridine

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Etoxeridine
Etoxeridine.svg
Systematic (IUPAC) name
ethyl 1-[2-(2-hydroxyethoxy)ethyl]-4-phenylpiperidine-4-carboxylate
Clinical data
Legal status Prohibited (S9) (AU) Class A (UK) Schedule I (US)
Identifiers
CAS number 469-82-9 YesY
ATC code None
PubChem CID 61122
DrugBank DB01505
ChemSpider 55070 YesY
UNII RHW35E1G7E YesY
Synonyms Etoxeridine, Carbetidine, Atenos
Chemical data
Formula C18H27NO4 
Mol. mass 321.41 g/mol
 YesY (what is this?)  (verify)

Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine).

Etoxeridine was developed in the 1950s[1] and investigated for use in surgical anesthesia, however it was never commercialised and is not currently used in medicine.[2][3][4]


References[edit]

  1. ^ BE Patent 558883
  2. ^ Merlevede E, Levis S. Pharmacological study of carbetidine, a new synthetic analgesic. (French). Archives Internationales de Pharmacodynamie et de Therapie. 1958 May 1;115(1-2):213-32.
  3. ^ Sironi PG. Brief note on a new synthetic analgesic: carbetidine hydrochloride. (Italian). Minerva Anestesiologica. 1959 Jun;25(6):251-4.
  4. ^ Crawford JS, Foldes FF. Studies on the respiratory and circulatory effects of carbetidine HCI used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia. British Journal of Anaesthesia. 1959 Aug;31:348-51.