As of October 2012, the song has sold over 2 million digital downloads. It also hit No. 7 on the Alternative Songs chart, their first Top 10 hit after Animal, it also hit No. 1 on the Adult Pop Songs, their first song to do so.
"Everybody Talks" was inspired by early 1960s pop music; Tyler Glenn said that "We fell in love with a lot of like Roy Orbison and the Motown music that my dad listens to." 
The song has received generally positive reviews from critics. PopCrush gave it 4 of 5 stars stating that "people can relate to 'Everybody Talks'." About.com said it was, "a song that will work with a very wide audience".
An animated music video to accompany the release of "Everybody Talks" was first released onto YouTube on January 14, 2012, at a total length of three minutes and forty-two seconds.
The real music video for "Everybody Talks" was released on VEVO and YouTube on March 8, 2012. It features the band at a 1950s-esque drive-in watching a movie called "Zombie Bikers From Hell." In the film, band members are playing music to the song inside a cabin when they're attacked by a group of zombies who are leather-clad motorcycle riders. Lead singer Tyler is the only one to escape, while the other band members are slaughtered by the zombies, offscreen, to the horror of the audience members at the drive-in.
Meanwhile, in the "real life" drive-in, a girl wearing red sunglasses starts seducing various male patrons. Once she and the men are alone in a secluded area, she reveals herself to be a fire-breathing vampire and eats them. In the film, Tyler hitches a ride from a girl in red-sunglasses. As they drive off in a white van, Tyler's fate remains unknown. However, Tyler, and the girl are present at the drive-in. The girl who drove up in the van at the end of the movie is the same girl who the band drove up to the cabin in.