Evodiamine
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Evodiamine
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| Systematic (IUPAC) name | |
| 21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one | |
| Identifiers | |
| CAS number | |
| ATC code | none |
| PubChem | |
| Chemical data | |
| Formula | C19H17N3O |
| Mol. mass | 303.36 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Evodiamine is a chemical which is extracted from the Evodia spp family of plants which has been shown to reduce fat uptake in mouse studies.[citation needed] Its method is believed to be similar to capsaicin, but retains none of the "hot" taste.[citation needed]
Evodiamine may interact with UCP1, which is a thermogenic protein that allows energy to be burned as heat.
[edit] References
- Kobayashi, Y. et al. (2001): Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. In: Planta Med. 67(7); 628–33; PMID 11582540
- Wang, T. et al. (2008): Evodiamine improves diet-induced obesity in an uncoupling protein-1-independent manner: involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling. In: Endocrinology 149(1); 358–66; PMID 17884939
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