Extraglomerular mesangial cell

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Renal corpuscle. Extraglomerular mesangial cell is #5b.

Extraglomerular mesangial cells (also known as Lacis cells, Goormaghtigh cells, or Polkissen cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.

Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the distal convoluted tubule and juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood, although it has been associated with the secretion of erythropoietin.[1]

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  1. ^ Junqueira, Luiz C.; Jose Carneiro (2003). Basic Histology. McGraw-Hill. ISBN 0-8385-0590-2.