Fluorodopa

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Fluorodopa
Fluorodopa.png
Systematic (IUPAC) name
2-fluoro-5-hydroxy-L-tyrosine
Clinical data
Identifiers
75290-51-6
ChemSpider 96897
Synonyms 6-fluoro-L-DOPA
FDOPA
Chemical data
Formula C9H10FNO4
215.18 g/mol

Fluorodopa, also known as FDOPA, is a fluorinated form of L-DOPA primarily synthesized as its fluorine-18 isotopologue for use as a radiotracer in positron emission tomography.[1] FD PET is a valid method for assessing the functional state of the nigrostriatal dopaminergic pathway. It is particularly useful for studies requiring repeated measures such as examinations of the course of a disease and the effect of treatment

References[edit]

  1. ^ Deng W-P, Wong KA, Kirk KL (2002). "Convenient syntheses of 2-, 5- and 6-fluoro- and 2,6-difluoro-L-DOPA". Tetrahedron: Asymmetry 13 (11): 1135–1140. doi:10.1016/S0957-4166(02)00321-X.