FGF13

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Fibroblast growth factor 13
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols FGF13 ; FGF-13; FGF2; FHF-2; FHF2
External IDs OMIM300070 MGI109178 HomoloGene3036 GeneCards: FGF13 Gene
RNA expression pattern
PBB GE FGF13 205110 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 2258 14168
Ensembl ENSG00000129682 ENSMUSG00000031137
UniProt Q92913 P70377
RefSeq (mRNA) NM_001139498 NM_010200
RefSeq (protein) NP_001132970 NP_034330
Location (UCSC) Chr X:
137.71 – 138.3 Mb
Chr X:
59.06 – 59.57 Mb
PubMed search [1] [2]

Fibroblast growth factor 13 is a protein that in humans is encoded by the FGF13 gene.[1][2]

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.[2]

References[edit]

  1. ^ Smallwood PM, Munoz-Sanjuan I, Tong P, Macke JP, Hendry SH, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (Oct 1996). "Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development". Proc Natl Acad Sci U S A 93 (18): 9850–7. doi:10.1073/pnas.93.18.9850. PMC 38518. PMID 8790420. 
  2. ^ a b "Entrez Gene: FGF13 fibroblast growth factor 13". 

Further reading[edit]