FGF22

From Wikipedia, the free encyclopedia
Jump to: navigation, search
fibroblast growth factor 22
Identifiers
Symbol FGF22
Entrez 27006
HUGO 3679
OMIM 605831
RefSeq NM_020637
UniProt Q9HCT0
Other data
Locus Chr. 19 p13.3

Fibroblast growth factor 22 is a protein which in humans is encoded by the FGF22 gene.[1][2]

Function[edit]

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.[3]

References[edit]

  1. ^ Umemori H, Linhoff MW, Ornitz DM, Sanes JR (July 2004). "FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain". Cell 118 (2): 257–70. doi:10.1016/j.cell.2004.06.025. PMID 15260994. 
  2. ^ Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM (June 2006). "Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family". The Journal of Biological Chemistry 281 (23): 15694–700. doi:10.1074/jbc.M601252200. PMC 2080618. PMID 16597617. 
  3. ^ "Entrez Gene: Fibroblast growth factor 22". 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.