FKBP10

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FK506 binding protein 10, 65 kDa
Identifiers
Symbols FKBP10 ; FKBP65; OI11; OI6; PPIASE; hFKBP65
External IDs OMIM607063 MGI104769 HomoloGene7718 GeneCards: FKBP10 Gene
EC number 5.2.1.8
RNA expression pattern
PBB GE FKBP10 219249 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 60681 14230
Ensembl ENSG00000141756 ENSMUSG00000001555
UniProt Q96AY3 Q61576
RefSeq (mRNA) NM_021939 NM_001163481
RefSeq (protein) NP_068758 NP_001156953
Location (UCSC) Chr 17:
39.97 – 39.98 Mb
Chr 11:
100.42 – 100.42 Mb
PubMed search [1] [2]

FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene.[1][2][3]

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase family. It is located in endoplasmic reticulum and acts as molecular chaperones. Two alternatively spliced variants, which encode different isoform, are reported.[3]

References[edit]

  1. ^ Patterson CE, Schaub T, Coleman EJ, Davis EC (Feb 2001). "Developmental Regulation of FKBP65: An ER-localized Extracellular Matrix Binding-Protein". Mol Biol Cell 11 (11): 3925–35. doi:10.1091/mbc.11.11.3925. PMC 15047. PMID 11071917. 
  2. ^ Ishikawa Y, Vranka J, Wirz J, Nagata K, Bachinger HP (Nov 2008). "The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens". J Biol Chem 283 (46): 31584–90. doi:10.1074/jbc.M802535200. PMID 18786928. 
  3. ^ a b "Entrez Gene: FKBP10 FK506 binding protein 10, 65 kDa". 

Further reading[edit]