FOSL2

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FOS-like antigen 2
Identifiers
Symbols FOSL2 ; FRA2
External IDs OMIM601575 MGI102858 HomoloGene3845 GeneCards: FOSL2 Gene
RNA expression pattern
PBB GE FOSL2 205409 at tn.png
PBB GE FOSL2 218880 at tn.png
PBB GE FOSL2 218881 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 2355 14284
Ensembl ENSG00000075426 ENSMUSG00000029135
UniProt P15408 P47930
RefSeq (mRNA) NM_005253 NM_008037
RefSeq (protein) NP_005244 NP_032063
Location (UCSC) Chr 2:
28.62 – 28.64 Mb
Chr 5:
32.14 – 32.16 Mb
PubMed search [1] [2]

Fos-related antigen 2 is a protein that in humans is encoded by the FOSL2 gene.[1]

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.