FOXK2

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Forkhead box K2
Protein FOXK2 PDB 1jxs.png
PDB rendering based on 1jxs.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols FOXK2 ; ILF; ILF-1; ILF1
External IDs OMIM147685 MGI1916087 HomoloGene18748 GeneCards: FOXK2 Gene
RNA expression pattern
PBB GE FOXK2 203064 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3607 68837
Ensembl ENSG00000261845 ENSMUSG00000039275
UniProt Q01167 Q3UCQ1
RefSeq (mRNA) NM_004514 NM_001080932
RefSeq (protein) NP_004505 NP_001074401
Location (UCSC) Chr 17:
80.56 – 80.56 Mb
Chr 11:
121.26 – 121.31 Mb
PubMed search [1] [2]

Forkhead box protein K2 is a protein that in humans is encoded by the FOXK2 gene.[1][2]

The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements.[2]

References[edit]

  1. ^ Durand DB, Shaw JP, Bush MR, Replogle RE, Belagaje R, Crabtree GR (Jul 1988). "Characterization of antigen receptor response elements within the interleukin-2 enhancer". Mol Cell Biol 8 (4): 1715–24. PMC 363332. PMID 3260003. 
  2. ^ a b "Entrez Gene: FOXK2 forkhead box K2". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.