FZD10

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Frizzled class receptor 10
Identifiers
Symbols FZD10 ; CD350; FZ-10; Fz10; FzE7; hFz10
External IDs OMIM606147 MGI2136761 HomoloGene21411 IUPHAR: FZD10 GeneCards: FZD10 Gene
RNA expression pattern
PBB GE FZD10 219764 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 11211 93897
Ensembl ENSG00000111432 ENSMUSG00000081683
UniProt Q9ULW2 Q8BKG4
RefSeq (mRNA) NM_007197 NM_175284
RefSeq (protein) NP_009128 NP_780493
Location (UCSC) Chr 12:
130.65 – 130.65 Mb
Chr 5:
128.6 – 128.6 Mb
PubMed search [1] [2]

Frizzled-10 is a protein that in humans is encoded by the FZD10 gene.[1][2] FZD10 has also been designated as CD350 (cluster of differentiation 350).

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.[2]

See also[edit]

References[edit]

  1. ^ Koike J, Takagi A, Miwa T, Hirai M, Terada M, Katoh M (Sep 1999). "Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family". Biochem Biophys Res Commun 262 (1): 39–43. doi:10.1006/bbrc.1999.1161. PMID 10448064. 
  2. ^ a b "Entrez Gene: FZD10 frizzled homolog 10 (Drosophila)". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.