In 1999, Franklin was hired to be an extra in the music video for Destiny's Child's "Bills, Bills, Bills". It was there that she met with group members Kelly Rowland, Beyoncé Knowles, LeToya Luckett, and LaTavia Roberson. At the time she was in a fledgling singing group called Jane Doe, which was in the process of disbanding. In December, Matthew Knowles invited Franklin and Michelle Williams to join Destiny's Child—replacing previous group members LaTavia Roberson and LeToya Luckett without notice. The two were introduced in February 2000 via the music video for "Say My Name". Franklin toured and performed with the group, and also appeared in the music video for "Jumpin', Jumpin'". Franklin contributed backing vocals to the remixes of "Jumpin', Jumpin'", "Independent Women Part I" (which were subsequently removed prior to the album release), "Independent Women Part II", "Dot", and "Dance with Me". In July 2000, after five months with Destiny's Child, Franklin was dismissed from the group, learning of her firing from an MTV News report. Shortly thereafter, group member Beyoncé Knowles stated in an interview that Franklin had missed three major dates and expressed a lack of interest in continuing with the group, leaving them with no other choice but to fire her.
After leaving Destiny's Child, Franklin began a solo career. She signed to and was dropped from Fo-reel Entertainment in 2002, where she recorded a song entitled "Get at Me" with Method Man. She was then signed and dropped from the Fabolous street label. She also began an acting career, and starred in The Brewster Project in 2004. She finished shooting an independent thriller film called Eyes of Darkness, which also features rapper Jayo Felony. Before joining Destiny's Child, Franklin also made an appearance in the 1999 feature film, Trippin'. Franklin has modeled for Russell Simmons' fashion line, Def Jam University and has been featured on the covers of Teen People, Ebony, Cosmo Girl, Vibe, and Today's Black Woman.
In early 2007, Franklin appeared with other former members of Destiny's Child in the E! special Boulevard of Broken Dreams, which documented their experiences in Destiny's Child and the issues which Franklin caused during the five months she was present in the group. Aside from appearing in music videos by Destiny's Child, she has also appeared in videos for Mr. Cheeks, and R. L. Huggar. She said in an interview that she has finished 13 songs for her album and is still choosing a single. She owns a company called One Love Pictures and Entertainment.
In April 2011, Franklin was arrested for disorderly conduct in Culver City, California. She later claimed that she was "manhandled" by police, the victim of racial profiling and had not been arrested but merely detained; however, police reiterated to TMZ that she was in fact arrested and that they were responding to a resident's claim that Franklin had been "disturbing the peace".