Fasiplon

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Fasiplon
Fasiplon structure.png
Systematic (IUPAC) name
6-Ethyl-7-methoxy-5-methyl-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-imidazo[1,2-a]pyrimidine
Clinical data
Legal status ?
Identifiers
CAS number 106100-65-6
ATC code None
PubChem CID 208954
ChemSpider 181047
UNII XCA050IPGB YesY
Chemical data
Formula C13H15N5O2 
Mol. mass 273.290 g/mol
 YesY (what is this?)  (verify)

Fasiplon is a nonbenzodiazepine anxiolytic drug from the imidazopyrimidine family of drugs.

Fasiplon binds strongly to benzodiazepine sites on the GABAA receptor and has similar anxiolytic effects in animals, but with less sedative or muscle relaxant action.[1] It was developed by a team at Roussel Ucla in the 1990s[2]

References[edit]

  1. ^ Tully WR, Gardner CR, Gillespie RJ, Westwood R (July 1991). "2-(oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors". Journal of Medicinal Chemistry 34 (7): 2060–7. doi:10.1021/jm00111a021. PMID 1648620. 
  2. ^ US Patent 5869481 Anticonvulsive 1-ar(alk)ylimidazolin-2-ones and process for making